tendοnitis

Tendοnitis: What it is, how long it lasts, and what role supplements play?

by George Chatzis, Dietician - Nutritionist, MSc

09 Mar 2026 • 0 min read

If you've ever experienced shoulder pain or elbow/knee pain and thought, "Tendοnitis... what should I take?", you're not alone. And that's where the classic dilemma begins:

Is there a pill for tendonitis?

What is the best ointment for tendonitis?

How long does tendonitis last?

The truth is that there are no "magic" solutions. However, there are scientifically proven supportive tools that you can add to your arsenal, along with the basics: proper rehabilitation.

Let's see what the research says.


Tendinitis or tendinopathy?

The term tendinitis is used for many conditions (shoulder, wrist, hand, elbow, knee). However, modern knowledge defines the condition as tendinopathy: a spectrum of tendon changes related to overload, poor load tolerance, microtrauma, and morphological reorganization—not always as the "classic" inflammation that goes away with anti-inflammatories. (Millar et al., 2021)

In simple terms:

The pain may encounter "inflammatory" elements, but the solution is usually to restore the tendon and make it capable of withstanding heavy loads again.

How long does tendonitis take to heal?

The question how long does tendonitis take to heal is the most common — and the most difficult to answer in a single sentence.

What affects recovery time:

How long the symptoms have been present (acute vs. chronic),

How much strain is placed on the tendon in your daily life (work/sports/ergonomics),

→ Whether proper progressive loading (recovery exercises) is being done,

→ The location: shoulder tendonitis, wrist tendonitis, elbow tendonitis, knee tendonitis, as they do not always behave in the same way,

→ Special forms such as calcific shoulder tendonitis.

General principle from the scientific literature: tendinopathy is a condition that improves with time and the right loading program, not just with the use of analgesics. (Millar et al., 2021; Knapik & Pope, 2020)

Where does it occur most often? (and what to expect)

Shoulder tendonitis

Shoulder tendonitis is often associated with the rotator cuff tendons. The central part of treatment is exercises (with progressive intensity and pain control). (Millar et al., 2021)

Calcific shoulder tendonitis

Calcific shoulder tendonitis can flare up with intense pain. In calcific tendinitis of the shoulder, exercises remain useful for function/mobility, but in some cases medical intervention is also necessary (depending on the stage and severity). (Millar et al., 2021)

Wrist tendonitis / hand tendonitis

Wrist tendonitis and hand tendonitis very often require: smart reduction of irritation (not complete immobility forever), as well as return with progressive strengthening.

Elbow tendonitis

Elbow tendonitis (also known as tennis elbow) usually responds to progressive strengthening of the extensors and smart activity management. (Millar et al., 2021)

Knee tendonitis

Knee tendonitis (e.g., patellar tendon) is often associated with jumping/running/stair climbing and requires a gradual loading plan. (Millar et al., 2021)

What should I take? Medications or ointments for tendonitis?

Is there a pill for tendonitis?

There are options for pain—but no magic pill that enhances the tendon's ability to withstand load. Tendinopathy is considered to be a problem of load tolerance, rather than a problem that can be solved with medication alone. (Millar et al., 2021)

Anti-inflammatory drugs for tendonitis

Anti-inflammatory drugs for tendonitis (NSAIDs) can be helpful:

→ During acute phases,

→ When pain prevents you from sleeping/working/starting rehabilitation.

But: they are not a stand-alone treatment. Their main purpose is to reduce pain so that the loading program can be properly implemented.

Anti-inflammatory cream for tendonitis

The best ointment for tendonitis in practice means: "What will help me with the pain?"

→ An anti-inflammatory cream for tendonitis (topical NSAID) can provide symptomatic relief, especially in superficial areas (e.g., elbow/wrist).

→ For tendonitis in the shoulder area, relief is often more limited, because the shoulder joint is more complex.

Safety note: In case of contraindications to the use of anti-inflammatory drugs (renal and/or gastrointestinal disease, anticoagulant therapy, etc.), careful guidance from the treating physician is required.

Dietary supplements: 4+1 scientifically proven options (without exaggeration)

1) Collagen peptides + exercise, the most "clear-cut" indication for tendinopathy.

In patients with Achilles tendinopathy, a study showed that collagen peptides combined with strengthening exercise led to enhanced functionality and reduced pain. (Praet et al., 2019)

2) Vitamin C (as support for natural collagen production & antioxidant after injuries)

Vitamin C is biologically related to collagen synthesis. A systematic review (DePhillipo et al., 2018) examined its effect on collagen production and oxidative stress, following musculoskeletal injuries, noting that in combination with the rehabilitation program, it contributed to a reduction in recovery time.

When attention is needed (and not "self-management")

Medical guidance is needed if there is:

→ A sudden "crack" with loss of strength,

→ Significant swelling/redness/fever,

→ Numbness/neurological symptoms,

→ Persistence/worsening, despite 2–4 weeks of proper management.

Healthcare professional guidance is crucial for dosage, duration, combinations, and outcome assessment.

In conclusion

For tendonitis:

  1. The basis is progressive rehabilitation with exercise and proper load management. (Millar et al., 2021)
  2. Anti-inflammatory drugs/ointments mainly help symptomatically so that rehabilitation can be as painless as possible.
  3. Among the supplements used, the most "clear" clinical signal for tendinopathy on the list is specific collagen peptides, in combination with exercise (Praet et al., 2019), with vitamin C as a logical support in the context of collagenogenesis/injuries (DePhillipo et al., 2018).

Disclaimer: This article is for informational purposes only and does not replace medical diagnosis or treatment. If you have underlying medical conditions, are pregnant/breastfeeding, or are taking medication, consult your doctor, pharmacist, or dietitian before starting any medication or supplements.



Scientific References

  1. Burton I, McCormack A. Nutritional Supplements in the Clinical Management of Tendinopathy: A Scoping Review. J Sport Rehabil. 2023 May 5;32(5):493-504. doi: 10.1123/jsr.2022-0244. PMID: 37146985.
  2. Chen B, Liang Y, Zhang J, Bai L, Xu M, Han Q, Han X, Xiu J, Li M, Zhou X, Guo B, Yin Z. Synergistic enhancement of tendon-to-bone healing via anti-inflammatory and pro-differentiation effects caused by sustained release of Mg2+/curcumin from injectable self-healing hydrogels. Theranostics. 2021 Apr 3;11(12):5911-5925. doi: 10.7150/thno.56266. PMID: 33897889; PMCID: PMC8058719.
  3.  DePhillipo NN, Aman ZS, Kennedy MI, Begley JP, Moatshe G, LaPrade RF. Efficacy of Vitamin C Supplementation on Collagen Synthesis and Oxidative Stress After Musculoskeletal Injuries: A Systematic Review. Orthop J Sports Med. 2018 Oct 25;6(10):2325967118804544. doi: 10.1177/2325967118804544. PMID: 30386805; PMCID: PMC6204628.
  4. Fusini F, Bisicchia S, Bottegoni C, Gigante A, Zanchini F, Busilacchi A. Nutraceutical supplement in the management of tendinopathies: a systematic review. Muscles Ligaments Tendons J. 2016 May 19;6(1):48-57. doi: 10.11138/mltj/2016.6.1.048. PMID: 27331031; PMCID: PMC4915461.
  5. Genç AS, Yılmaz AK, Anıl B, Korkmaz Salkılıç E, Akdemir E, Sancaklı A, Mor A, Ermiş E, Baraz LS, Güzel N, Kehribar L. Effect of supplementation with type 1 and type 3 collagen peptide and type 2 hydrolyzed collagen on osteoarthritis-related pain, quality of life, and physical function: A double-blind, randomized, placebo-controlled study. Jt Dis Relat Surg. 2025 Jan 2;36(1):85-96. doi: 10.52312/jdrs.2025.1965. Epub 2024 Nov 5. PMID: 39719905; PMCID: PMC11734850.
  6. Hausenblas H, Hooper D, Hooper S. Effectiveness of Cucumis sativus L. Supplementation on Mild to Moderate Joint Pain: A Randomized, Double-Blind, Placebo-Controlled Study. Cureus. 2025 Sep 29;17(9):e93507. doi: 10.7759/cureus.93507. PMID: 41040766; PMCID: PMC12486685.
  7. Knapik JJ, Pope R. Achilles Tendinopathy: Pathophysiology, Epidemiology, Diagnosis, Treatment, Prevention, and Screening. J Spec Oper Med. 2020 Spring;20(1):125-140. doi: 10.55460/QXTX-A72P. PMID: 32203618.
  8. König D, Oesser S, Scharla S, Zdzieblik D, Gollhofer A. Specific Collagen Peptides Improve Bone Mineral Density and Bone Markers in Postmenopausal Women-A Randomized Controlled Study. Nutrients. 2018 Jan 16;10(1):97. doi: 10.3390/nu10010097. PMID: 29337906; PMCID: PMC5793325.
  9. Lugo JP, Saiyed ZM, Lau FC, Molina JP, Pakdaman MN, Shamie AN, Udani JK. Undenatured type II collagen (UC-II®) for joint support: a randomized, double-blind, placebo-controlled study in healthy volunteers. J Int Soc Sports Nutr. 2013 Oct 24;10(1):48. doi: 10.1186/1550-2783-10-48. PMID: 24153020; PMCID: PMC4015808.
  10. Millar NL, Silbernagel KG, Thorborg K, Kirwan PD, Galatz LM, Abrams GD, Murrell GAC, McInnes IB, Rodeo SA. Tendinopathy. Nat Rev Dis Primers. 2021 Jan 7;7(1):1. doi: 10.1038/s41572-020-00234-1. Erratum in: Nat Rev Dis Primers. 2021 Feb 3;7(1):10. doi: 10.1038/s41572-021-00251-8. PMID: 33414454.
  11. Praet SFE, Purdam CR, Welvaert M, Vlahovich N, Lovell G, Burke LM, Gaida JE, Manzanero S, Hughes D, Waddington G. Oral Supplementation of Specific Collagen Peptides Combined with Calf-Strengthening Exercises Enhances Function and Reduces Pain in Achilles Tendinopathy Patients. Nutrients. 2019 Jan 2;11(1):76. doi: 10.3390/nu11010076. PMID: 30609761; PMCID: PMC6356409.
  12. Saab M, Hildebrand F, Martel B, Blanchemain N. Osteoinductive Bone Morphogenic Protein, Collagen Scaffold, Calcium Phosphate Cement, and Magnesium-Based Fixation Enhance Anterior Cruciate Ligament Tendon Graft to Bone Healing In Animal Models: A Systematic Review. Arthroscopy. 2023 Feb;39(2):529-548.e9. doi: 10.1016/j.arthro.2022.05.011. Epub 2022 Jun 15. PMID: 35714968.
  13. Schön C, Knaub K, Alt W, Durkee S, Saiyed Z, Juturu V. UC-II Undenatured Type II Collagen for Knee Joint Flexibility: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Clinical Study. J Integr Complement Med. 2022 Jun;28(6):540-548. doi: 10.1089/jicm.2021.0365. Epub 2022 Apr 4. PMID: 35377244; PMCID: PMC9232232.
*Text editing: Maria Kirmanidou

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